Silk Fibroin: A Promising Tool for Wound Healing and Skin Regeneration

Silk is a functional protein biomaterial produced by variety of insects like flies, silkworms, scorpions, spiders, and mites. synthesized silkworms extensively studied for its applications in tissue engineering wound healing. undoubtedly natural biocompatible material with humans has role medical treatments from ancient times. The silk worm comprises two types proteins namely fibroin sericin. makes up approximately 70% cocoon weight wide textiles all biomedical owing to biocompatible, nontoxic, biodegradable, less immunogenic, noncarcinogenic nature. It possesses outstanding toughness mechanical strength, while sericin high defensive ability against ultraviolet light oxidation. been known induce healing increasing cell proliferation growth migrating various cells which are involved different stages process. With several varieties fibroin, sericin, recombinant materials, native spider have investigated over the last decades. an objective harnessing regenerative properties, plentiful strategies applied develop bioartificial skin grafts bioactive dressings recent This review gives detailed insight into structure, general structure-properties relationship, fibroin.